The Mandalay Bay complex (includes the Luxor and Excalibur) is the place to be for me. Everything you need under one roof....best sports book in Vegas, great restaurants, fantastic entertainment (be sure to catch Criss Angel if you can get a ticket), outstanding casino. "The Hotel" is posh beyond belief if you can afford it. If you want hookers and strippers it may not be the best place to be but there are thousands of cabs in LV that can take you anywhere you want to go.