********* of estrogen in a long-term high dose fashion is EXECUTION BY LETHAL ********* OF THE MOST POTENT DANGEROUS CHEMICAL-ESTROGEN.
DEATH BY ********* OF ESTROGEN !
"what are all the good and bad effects of high estrogen in a man???
what can it do to a man ?
a) Adverse effects of estrogen in men
High levels of estrogen can cause reduced
levels of testosterone, fatigue, loss of muscle tone, increased body
fat, loss of libido and sexual function and an enlarged prostate.
Other problems associated with excessive levels of estrogen include
(1) The shut down of normal testicular production of testosterone.
Excess estrogen can saturate testosterone receptors in the
hypothalamus in the brain therefore reducing the signal sent to the
pituitary gland. This in turn reduces the secretion of luteinizing
hormone, which is necessary for the gonads to produce testosterone.
(2) Increasing the body's production of sex hormone-binding globulin
(SHBG). SHBG binds testosterone therefore reducing the amount of the
clinical important free testosterone in the ***** available to cell
receptor sites.
(3) A reduced effectiveness of the testosterone replacement therapy
due to excess aromatization of testosterone medications to estrogen.
(4) Long-term health risks including an increased risk of diabetes,
heart disease, and some cancers."
http://www.smart-*****.net/ias-estrogen.htm
From RenewYouth:
"Estrogen is a necessary hormone for men, but too much causes a wide
range of health problems. The most dangerous acute effect of excess
estrogen and too little testosterone is an increased risk of heart
****** or stroke. High levels of estrogen have been implicated as a
cause of benign prostatic hypertrophy (BPH) and one mechanism by which
nettle extract works is to block the binding of growth-stimulating
estrogen to prostate cells.
From the **** Information Handbook, a comprehensive description of
adverse effects is given (obviously some of the risks are
female-specific):
Use with caution in patients with a history of
hypercalcemia, cardiovascular disease, and gallbladder disease.
May increase ***** pressure. Use with caution in patients with hepatic
disease. May increase risk of venous thromboembolism. Estrogens may
increase the risk of breast cancer estrogen are generally associated with lipid effects such as increased HDL-cholesterol and decreased LDL-cholesterol.
Triglycerides may also be increased; use with caution in patients with
familial defects of lipoprotein metabolism. Estrogens may cause
premature closure of the epiphyses in young individuals.
ADVERSE REACTIONS — Frequency not defined.
Cardiovascular: Edema, hypertension, venous thromboembolism
Central nervous system: Dizziness, headache, mental depression,
migraine
Dermatologic: Chloasma, erythema multiforme, erythema nodosum,
hemorrhagic eruption, hirsutism, loss of scalp hair, melasma
Endocrine & metabolic: Breast enlargement, breast tenderness, changes
in libido, increased thyroid-binding globulin, increased total thyroid
hormone (T4), increased serum triglycerides/phospholipids, increased
HDL-cholesterol, decreased LDL-cholesterol, impaired glucose
tolerance, hypercalcemia
Gastrointestinal: Abdominal cramps, bloating, cholecystitis,
cholelithiasis, gallbladder disease, nausea, pancreatitis, ********,
weight gain/loss
Genitourinary: Alterations in frequency and flow of menses, changes in
cervical secretions, endometrial cancer, increased size of uterine
leiomyomata, vaginal candidiasis
Hematologic: Aggravation of porphyria, decreased antithrombin III and
antifactor Xa, increased levels of fibrinogen, increased platelet
aggregability and platelet count; increased prothrombin and factors
VII, VIII, IX, X
Hepatic: Cholestatic jaundice
Neuromuscular & skeletal: Chorea
Ocular: Intolerance to contact lenses, steeping of corneal curvature
Respiratory: Pulmonary thromboembolism
Miscellaneous: Carbohydrate intolerance
CARDIOVASCULAR CONSIDERATIONS — It is important to recognize that
estrogens may induce or worsen hypertension. These problems are less
severe with lower doses. Furthermore, estrogens may precipitate
thromboembolic events, particularly in women who smoke. It is
important that patients on long-term estrogens undergo monitoring of
***** pressure and avoid cigarette use." (1)
UptoDate discusses some complications of increased estrogens in men:
"The most life-threatening complications are cardiovascular sequelae,
which include myocardial infarction, cerebrovascular accident, and
pulmonary embolism. As with most androgen ablation therapies,
estrogens are associated with a loss of libido, impotence, and
lethargy. Gynecomastia and nipple soreness can be particularly
troublesome and can be avoided to some extent by prophylactic breast
irradiation. Prophylactic therapy may be necessary because
gynecomastia and nipple tenderness do not respond well to irradiation
once estrogen therapy is begun, and usually persist even if estrogen
is discontinued." (2)