Amazon have it listed for the end of March 2008, but I think it'll be delayed.
Anyway the graphics look very pretty and there's an intense trailer on Live, but I haven't seen any gameplay footage, nor have I heard what the damage system is going to be (Healthpacks, regeneration etc).
I wonder if CapCom are going to deliver a dated product with a nice next-gen sheen. I am interested in the look of this game, although the first two entries in the series bored the hell outta me.
Big twist in the game? Will your character become infected? Become more than human like Matthew Kane in Quake 4 or Jack Carver in FarCry Instincts?
I'll have to keep waiting.