I have an old school Boss GT-8 multi effect units and you can change the order of effects. I am sure Line 6 is the same.That was a great video, and it answered a lot of questions I've always wondered about. Although a lot of players now a days are using those multi-effects units by Boss, or Line 6. I don't know if you can program those to work in an order you want, like you could with a stomp box set up. My guitar amp is a Line 6 modeling amp, and it sounds good, for what I do, which is just to tinker around, but it does combine more then one effect in the same knob. To be honest, I never read the manual, because I'm more into the bass then a 6-string, but I got it on sale for $349.00, and it's a 75 watt, 1-12 Spider.
I mainly play bass guitar too. Ever tried a 6 string bass?